Beneficial Effects of Chrysanthemum: Eye IrritationVolatile oil and flavonoids are believed to be main active components in Chrysanthemum morifolium Ramat.
Flavonoids, in the forms of glycoside derivatives, are more polar than volatile oil and hence are readily dissolved in water. This is partly the reason that most of the studies in chrysanthemum have been focused on its flavonoids.
Hot water extraction of chrysanthemum has been reported to show inhibitory activity against rat lens aldose reductase.
Flavones and flavones glycosides were found to be active components responsible for this observation, among which elaggic acid showed the highest inhibitory activity.
Elevated concentration of sorbitol is responsible for eye irritation.
Aldose reductase, along with coenzyme nicotinamide adenine dinucleotide phosphate (NADPH), catalyzes the reduction of glucose to sorbitol.
Beneficial Effects of Chrysanthemum: Eye Irritation
